Most recent advances in sequencing have celebrated the big picture: the successful mapping, for example, of entire genomes or large, significant series of gene.
In a paper published in the July 22 issue of Nature Biotechnology, an international team of researchers that includes Gregory A. Daniels at the UC San Diego Moores Cancer Center and Louise C. Laurant in the UCSD School of Medicine’s Department of Reproductive Medicine uses a novel sequencing method called Smart-Seq to deeply scrutinize the genetic information contained in a single cell.
The achievement is important. Many clinically relevant cells exist in only small numbers and require singular analysis. “Cancer researchers around the world will now be able to analyze these cells more systematically to enable them to produce better methods of diagnosis and therapy in the future,” said senior study author Rickard Sandberg of the Ludwig Institute for Cancer Research and Karolinska Institutet in Sweden.
You can read the full news release from LICR here.
Pictured: A prostate cancer cell